HPB Research and Publications

Fellows will take part in a mandatory clinical and translational research requirement. Virginia Mason's robust academic environment gives a breadth of opportunities in research. The Digestive Disease Institute, Floyd and Delores Jones Cancer Institute and Benaroya Research Institute provide an outstanding resource for our fellows.

Recent Publications

Peer-reviewed Publications

1. Surgical strategies and novel therapies for locally advanced pancreatic cancer.
Abou-Khalil J, Rocha FG.
J Surg Oncol. 2017 Jul;116(1):16-24. doi: 10.1002/jso.24654. Epub 2017 May 17. Review.
PMID: 28513899
 
2. What is a better predictor of clinically relevant postoperative pancreatic fistula (CR-POPF) following pancreaticoduodenectomy (PD): postoperative day one drain amylase (POD1DA) or the fistula risk score (FRS)?
Bertens KA, Crown A, Clanton J, Alemi F, Alseidi AA, Biehl T, Helton WS, Rocha FG.
HPB (Oxford). 2017 Jan;19(1):75-81. doi: 10.1016/j.hpb.2016.10.001. Epub 2016 Nov 4.
PMID: 27825541
 
3. Multidisciplinary management of locally advanced pancreatic ductal adenocarcinoma.
Alemi F, Alseidi A, Scott Helton W, Rocha FG.
Curr Probl Surg. 2015 Sep;52(9):362-98. doi: 10.1067/j.cpsurg.2015.07.003. Epub 2015 Jul 17. Review. No abstract available.
PMID: 26363649
 
4. Validation of Fistula Risk Score calculator in diverse North American HPB practices.
Grendar J, Jutric Z, Leal JN, Ball CG, Bertens K, Dixon E, Hammill CW, Kastenberg Z, Newell PH, Rocha F, Visser B, Wolf RF, Hansen PD.
HPB (Oxford). 2017 Jun;19(6):508-514. doi: 10.1016/j.hpb.2017.01.021. Epub 2017 Feb 21.
PMID: 28233672
 
5. Five-Year Actual Overall Survival in Resected Pancreatic Cancer: A Contemporary Single-Institution Experience from a Multidisciplinary Perspective.
Picozzi VJ, Oh SY, Edwards A, Mandelson MT, Dorer R, Rocha FG, Alseidi A, Biehl T, Traverso LW, Helton WS, Kozarek RA.
Ann Surg Oncol. 2017 Jun;24(6):1722-1730. doi: 10.1245/s10434-016-5716-z. Epub 2017 Jan 4.
PMID: 28054192
 
6. What is a better predictor of clinically relevant postoperative pancreatic fistula (CR-POPF) following pancreaticoduodenectomy (PD): postoperative day one drain amylase (POD1DA) or the fistula risk score (FRS)?
Bertens KA, Crown A, Clanton J, Alemi F, Alseidi AA, Biehl T, Helton WS, Rocha FG.
HPB (Oxford). 2017 Jan;19(1):75-81. doi: 10.1016/j.hpb.2016.10.001. Epub 2016 Nov 4.
PMID: 27825541
 
7. Using Experience-Based Design to Improve the Care Experience for Patients With Pancreatic Cancer.
Hagensen A, London AE, Phillips JJ, Helton WS, Picozzi VJ, Blackmore CC.
J Oncol Pract. 2016 Dec;12(12):e1035-e1041. Epub 2016 Sep 30.
PMID: 27624947
 
8. Classification and techniques of en bloc venous reconstruction for pancreaticoduodenectomy.
Alemi F, Rocha FG, Helton WS, Biehl T, Alseidi A.
HPB (Oxford). 2016 Oct;18(10):827-834. doi: 10.1016/j.hpb.2016.05.015. Epub 2016 Jul 12. Review.
PMID: 27506994
 
9. Localized pancreatic cancer with positive peritoneal cytology as a sole manifestation of metastatic disease: a single-institution experience.
Oh SY, Edwards A, Mandelson MT, Hahn H, Alseidi A, Biehl T, Kozarek RA, Rocha FG, Helton S, Picozzi VJ.
Am J Surg. 2017 Jan;213(1):94-99. doi: 10.1016/j.amjsurg.2016.04.008. Epub 2016 Jun 12.
PMID: 27424044
 
10. Studies address metabolic image-directed oncologic therapy for gastric cancer.
Rocha FG, Boughey JC.
Bull Am Coll Surg. 2016 May;101(5):48-50. No abstract available.
PMID: 27311237
 
11. Preoperative computed tomography scan to predict pancreatic fistula after distal pancreatectomy using gland and tumor characteristics.
Jutric Z, Johnston WC, Grendar J, Haykin L, Mathews C, Harmon LK, Shen J, Hahn HP, Coy DL, Cassera MA, Helton WS, Rocha FG, Wolf RF, Hansen PD, Hammill CW, Alseidi AA, Newell PH.
Am J Surg. 2016 May;211(5):871-6. doi: 10.1016/j.amjsurg.2016.02.001. Epub 2016 Feb 23.
PMID: 27046794
 
12. Local resection for duodenal gastrointestinal stromal tumors.
Crown A, Biehl TR, Rocha FG.
Am J Surg. 2016 May;211(5):867-70. doi: 10.1016/j.amjsurg.2016.02.006. Epub 2016 Mar 3.
PMID: 27033254
 
13. The Role of Biliary Carcinoembryonic Antigen-Related Cellular Adhesion Molecule 6 (CEACAM6) as a Biomarker in Cholangiocarcinoma.
Rose JB, Correa-Gallego C, Li Y, Nelson J, Alseidi A, Helton WS, Allen PJ, D'Angelica MI, DeMatteo RP, Fong Y, Kingham TP, Kowdley KV, Jarnagin WR, Rocha FG.
PLoS One. 2016 Mar 14;11(3):e0150195. doi: 10.1371/journal.pone.0150195. eCollection 2016.
PMID: 26974538
 
14. Extended right hepatectomy with caudate lobe resection using the hilar "en bloc" resection technique with a modified hanging maneuver.
Perini MV, Coelho FF, Kruger JA, Rocha FG, Herman P.
J Surg Oncol. 2016 Mar;113(4):427-31. doi: 10.1002/jso.24154. Epub 2016 Jan 18.
PMID: 26776500
 
15. Rare long-term survivors of pancreatic adenocarcinoma without curative resection.
Oh SY, Edwards A, Mandelson MT, Lin B, Dorer R, Helton WS, Kozarek RA, Picozzi VJ.
World J Gastroenterol. 2015 Dec 28;21(48):13574-81. doi: 10.3748/wjg.v21.i48.13574.
PMID: 26730170
 
16. Multidisciplinary management of locally advanced pancreatic ductal adenocarcinoma.
Alemi F, Alseidi A, Scott Helton W, Rocha FG.
Curr Probl Surg. 2015 Sep;52(9):362-98. doi: 10.1067/j.cpsurg.2015.07.003. Epub 2015 Jul 17. Review. No abstract available.
PMID: 26363649
 
17. Disparities in care for patients with curable hepatocellular carcinoma.
Burman B, Helton WS.
HPB (Oxford). 2015 Sep;17(9):745-6. doi: 10.1111/hpb.12477. No abstract available.
PMID: 26278320
 
18. Hybrid push-pull endoscopic and laparoscopic full thickness resection for the minimally invasive management of gastrointestinal stromal tumors: a pilot clinical study.
Willingham FF, Reynolds P, Lewis M, Ross A, Maithel SK, Rocha FG.
Gastroenterol Res Pract. 2015;2015:618756. doi: 10.1155/2015/618756. Epub 2015 Apr 6.
PMID: 25945087
 
19. Interferon-based Adjuvant Chemoradiation for Resected Pancreatic Head Cancer: Long-term Follow-up of the Virginia Mason Protocol.
Rocha FG, Hashimoto Y, Traverso LW, Dorer R, Kozarek R, Helton WS, Picozzi VJ.
Ann Surg. 2016 Feb;263(2):376-84. doi: 10.1097/SLA.0000000000001190.
PMID: 25775069
 
20. Less invasive option for small hepatocellular carcinoma: thermal ablation as first-line therapy?
Rocha FG, Boughey JC, Nelson H.
Bull Am Coll Surg. 2014 Feb;99(2):46-8. No abstract available.
PMID: 24564022
 
21. Extended neoadjuvant chemotherapy for borderline resectable pancreatic cancer demonstrates promising postoperative outcomes and survival.
Rose JB, Rocha FG, Alseidi A, Biehl T, Moonka R, Ryan JA, Lin B, Picozzi V, Helton S.
Ann Surg Oncol. 2014 May;21(5):1530-7. doi: 10.1245/s10434-014-3486-z. Epub 2014 Jan 29. Erratum in: Ann Surg Oncol. 2014 May;21(5):1538. Dosage error in article text.
PMID: 24473642
 
22. Posterior 'superior mesenteric artery first' approach for resection of locally advanced pancreatic cancer.
Rose JB, Rocha F, Alseidi A, Helton S.
Ann Surg Oncol. 2014 Jun;21(6):1927-8. doi: 10.1245/s10434-013-3431-6. Epub 2013 Dec 27.
PMID: 24370905
 
23. Dual-modality drainage of infected and symptomatic walled-off pancreatic necrosis: long-term clinical outcomes.
Ross AS, Irani S, Gan SI, Rocha F, Siegal J, Fotoohi M, Hauptmann E, Robinson D, Crane R, Kozarek R, Gluck M.
Gastrointest Endosc. 2014 Jun;79(6):929-35. doi: 10.1016/j.gie.2013.10.014. Epub 2013 Nov 15.
PMID: 24246792

24. Rocha FG, Helton WS. Resectability of colorectal liver metastases: an evolving definition. HPB (Oxford). 2012 May; 14(5):283-4. Epub. March 2012.

25. Bellows CF, Smith A, Malsbury J, Helton WS. Repair of incisional hernias with biological prosthesis: a systematic review of current evidence. In Press, The American J. Surgery. 2012

27. Betancourt-Ramirez A., Alkhoury F, McLaughlin CM,  WS Helton.  EnSeal™ vs. Conventional Ferguson Hemorrhoidectomy: Cost and Clinical Outcomes. Submitted, Diseases of Colon Rectum, 2013.

28. Lindeman BM, Lipsett PA, Alseidi A, Lidor AO. Medical student Sub-internships in Surgery: characterization and needs assessment. Am J Surg. 2013 Feb; 205 (2):175-81.

29. Seabott, H., Smith, R., Alseidi A. et al, The Surgical Residency Interview: A Candidate-Centered, Working Approach" Journal of Surgical Education.  November/December 2012   issue, volume 69(6).

30. Rowland, P., Alseidi A. et al., The Certifying Examination of the American Board of Surgery: The Effect of Improving Communication & Professional Competency: Twenty-Year Results. The Journal of Surgical Education. 2012 Jan-Feb;69(1):118-25.

31. Chapman, W. and A. Alseidi, Liver, in Essentials of General Surgery, R. Bell, Lawrence, and M. Dayton, Editors. 2012, Lippincott Williams & Wilkins.

Original Articles and Book Chapters

1. Damle, S. Symptomatic Walled-off Pancreatic Necrosis--Is there a Role for the Surgeon? Long oral presentation at the 2013 Americas Hepatopancreatobiliary Association Annual Meeting. Miami Beach, FL. March 7, 2012.

2. Damle S., Helton WS. Making Hepatic Trisectionectomies in Cholangiocarcinoma Safer by Retaining Sub-Segment 4A. Poster presentation at the 2013 Americas Hepatopancreatobiliary Association annual meeting in Miami, FL.

3. Helton WS, Koehler R, Fotoohi M, Alseidi A, Rocha F, Biehl T. Transthoracic transdiaphragmatic videoscopic-assisted microwave ablation (MWA) of small HCC in segment VII. Americas Hepato-Pancreato-Biliary Foundation Annual Congress. Miami Beach, FL. March 7, 2012.

4. Bellows C, Fitzgibbons R, Martindale R, Shadduck P, Collins J, Bochicchio G, Awad S, Helton S, Kaml G, Jain A, Smiell J, Rutan R. Prospective Randomized, Multicenter Study of Strattice™ Reconstructive Tissue Matrix in the Repair of Inguinal Hernias (RING): Month 12 Update. Presented at the 5th International Hernia Congress. New York, NY. March 28, 2012.

5. J. B. Rose, F. Rocha, A. Alseidi, T. Biehl, R. Moonka, J. Ryan, B. Lin, V. Picozzi, W S. Helton. Extended Neoadjuvant chemotherapy for borderline resectable pancreatic cancer demonstrates promising postoperative outcomes and survival. AHPBA, Feb 22, 2013. Miami, FL.

6. S. Damle, A. Alseidi, T. R. Biehl, W. S. Helton, R. Moonka, E. J. Raker, D. Neuzil, D. S. Pierce, F. G. Rocha. Management of Celiac Artery Stenosis in Pancreaticoduodenectomy. AHPBA, Feb 22, 2013. Miami, FL.

7. John B Rose III, Camilo Correa-Gallego, James Nelson, Adnan Alseidi, W. Scott Helton, Peter J Allen, Michael D'Angelica, Ronald P. DeMatteo, Yuman Fong, T. Peter Kingham, Kris Kowdley, William R. Jarnagin, Flavio G. Rocha. Role of biliary CEACAM6 as a biomarker for cholangiocarcinoma. ASCO 2013.

8. Damle S, Helton WS. Enucleation of IPMN of pancreatic head. Presented at Seattle Surgical Society Annual Meeting, January 11, 2013.

9. John B. Rose III, Flavio G. Rocha, Bruce S. Lin, Adnan Alseidi, Thomas Biehl, Ravi Moonka, John A. Ryan, L William Traverso, Scott Helton, Vincent J. Picozzi. Extended neoadjuvant chemotherapy (CT) in borderline resectable pancreas cancer (BRPC). Presented ASCO, 2013.

10. Smith, R., Seabott, H., Alseidi, A., The Working Interview Approach: Interviewing Applicants for General Surgery Residency. Alliance of Independent Academic Medical Centers.  Tucson, AZ; March 2012.

11. Lindeman, B., Lidor, A., Alseidi, A., et al, Medical Student Sub-Internships in Surgery: Characterization and Needs Assessment. American Program Directors of Surgery & Association of Surgical Education Joint Annual Meeting. March 2012. San Diego, CA.

12. Copeland, H., Alseidi, A., et al.: When Assessing The 3rd Year General Surgery Clerkship Trauma. Rotation: Are We Meeting The Learners’ Needs? 7th Academic Surgical Congress. Feb 2012. Las  Vegas, NV.

13. Gerald, S., Alseidi, A., et al: Management of locally aggressive foregut tumors in the setting of sinistral portal hypertension; The role of the RAMPS procedure. Seattle Surgical Society Annual meeting, Westin Hotel, Seattle, Jan 2012.

14. Bilderback PA, Helton WS. Practice Patterns for Bowel Obstruction by Washington State American College of Surgeons Members. Submitted, American College of Surgeons Annual Meeting, Washington, D.C. October 2013.

Book Chapters

1. WS Helton. Pancreatic Head Resection and Pancreaticojejunostomy for Chronic Pancreatitis. ACS Multimedia Atlas of Surgery. Pancreas Surgery Volume. Editors: Pascal, Fuchshuber & Horacio Aspun. Pg 119, 2012.

2. Bilderback PA, Smith RK, Helton WS. Intestinal Obstruction.  In: Scientific American Surgery. Scientific American Medicine, American College of Surgeons.  2012.

3. Rose JB, Helton WS. Abdominal Ultrasound for Surgeons. Editors: Ellen J. Hagopian and Junji Machi. New York: Springer Science and Business Media. (In Press, 2013).

4. Alseidi A. et al, Management of bile duct injuries, in Common Problems in Acute Care Surgery. Laura J., Turner, Krista L., and Todd, S. Rob, Editors. 2013, Springer-Verlag New York Inc.
 

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