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Published Digestive Disease Articles

The quality, multidisciplinary patient care and original research of the Digestive Disease Institute team is published and presented each year in hundreds of original papers and book chapters and at regional, national and international conferences. See a partial list of recent articles, abstracts and book chapters below. Additionally, the Digestive Disease Institute sponsors numerous patient databases, ranging in topic from Inflammatory Bowel Disease to Colon Cancer Screening, that supports both research and patient quality initiatives.

Congratulations to gastroenterologist Shayan Irani, MD, on being selected to join the Editorial Committee of Gastrointestinal Intervention, the official journal of the Society of Gastrointestinal Intervention

Bariatric

  • El Lakis MA, Pozzi A, Chamieh J, Safadi B. Portomesenteric vein thrombosis after laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass: a 36-case series. Surg Endosc 2016;(E-pub ahead of print.). https://www.ncbi.nlm.nih.gov/pubmed/27387181

Colon

  • Alvimopan Use, Outcomes, and Costs: A Report from the Surgical Care and Outcomes Assessment Program Comparative Effectiveness Research Translation Network Collaborative. Colorectal Writing Group for the SCOAP-CERTAIN Collaborative., Ehlers AP, Simianu VV, Bastawrous AL, Billingham RP, Davidson GH, Fichera A, Florence MG, Menon R, Thirlby RC, Flum DR, Farjah F. J Am Coll Surg. 2016 May;222(5):870-7. https://www.ncbi.nlm.nih.gov/pubmed/27113517
  • Kumar AS. In constant pursuit of improvements in rectal cancer care. VMMC Bull 2016;(2):8-12. https://www.ncbi.nlm.nih.gov/pubmed/26919270
  • Simianu VV, Basu A, Alfonso-Cristancho R, Thirlby RC, Flaxman AD, Flum DR. Assessing surgeon behavior change after anastomotic leak in colorectal surgery. J Surg Res 2016;205(2):378-383. https://www.ncbi.nlm.nih.gov/pubmed/27664886
  • Simianu VV, Fichera A, Bastawrous AL, Davidson GH, Florence MG, Thirlby RC, Flum DR. Number of Diverticulitis Episodes Before Resection and Factors Associated With Earlier Interventions. JAMA Surg. 2016 Jul 1;151(7):604-10. https://www.ncbi.nlm.nih.gov/pubmed/26864286
  • Simianu VV, Strate LL, Billingham RP, Fichera A, Steele SR, Thirlby RC, Flum DR. The Impact of Elective Colon Resection on Rates of Emergency Surgery for Diverticulitis. Ann Surg. 2016 Jan;263(1):123-9. https://www.ncbi.nlm.nih.gov/pubmed/26111203
  • Thornblade LW, Varghese TK Jr, Shi X, Johnson EK, Bastawrous A, Billingham RP, Thirlby R, Fichera A, Flum DR. Preoperative immunonutrition and elective colorectal resection outcomes. Dis Colon Rectum 2017;60(1):68-75. https://www.ncbi.nlm.nih.gov/pubmed/27926559
  • Cha JM, Kozarek RA, La Selva D, Gluck M, Ross A, Chiorean M, Koch J, Lin OS. Risks and Benefits of Colonoscopy in Patients 90 Years or Older, Compared With Younger Patients. Clin Gastroenterol Hepatol. 2016 Jan;14(1):80-6.e1. https://www.ncbi.nlm.nih.gov/pubmed/26164224
  • Lin OS, La Selva D, Cha JM, Gluck M, Ross A, Chiorean M, Kozarek RA. Validation of colonoscopic findings from a structured endoscopic documentation database against manually collected medical records data. Surg Endosc. 2016 Apr;30(4):1607-13. https://www.ncbi.nlm.nih.gov/pubmed/26173545

Book Chapters

Koch J, Lin OS. Issues in Colonoscopy in Elderly Patients (2017). In: Katlic M, ed. Pelvic Floor Dysfunction and Pelvic Surgery in the Elderly: An Integrated Approach (Springer Science Media, New York). http://www.springer.com/us/book/9781493965526

Esophageal Disorders

  • Kozarek RA. Self-Expandable Stents for Benign Esophageal Disorders: When do the Benefits Outweigh the Risks? J Clin Gastroenterol. 2016 May-Jun;50(5):357-8. https://www.ncbi.nlm.nih.gov/pubmed/26974754
  • Mohiuddin K, Dorer R, El Lakis MA, Hahn H, Speicher J, Hubka M, Low DE. Outcomes of Surgical Resection of T1bN0 Esophageal Cancer and Assessment of Endoscopic Mucosal Resection for Identifying Low-Risk Cancers Appropriate for Endoscopic Therapy. Ann Surg Oncol. 2016 Aug;23(8):2673-8. https://www.ncbi.nlm.nih.gov/pubmed/27020584
  • Zaninotto G, Low DE. Complications after esophagectomy: it is time to speak the same language. Dis Esophagus. 2016 Aug;29(6):580-2. https://www.ncbi.nlm.nih.gov/pubmed/26043784

General Surgery

  • Ehlers AP, Simianu VV, Bastawrous AL, Billingham RP, Davidson GH, Fichera A, Florence MG, Menon R, Thirlby RC, Flum DR, Farjah F. Alvimopan Use, Outcomes, and Costs: A Report from the Surgical Care and Outcomes Assessment Program Comparative Effectiveness Research Translation Network Collaborative. J Am Coll Surg 2016;222:870-877. https://www.ncbi.nlm.nih.gov/pubmed/27113517

  • Minami CA, Sheils CR, Bilimoria KY, Johnson JK, Berger ER, Berian JR, Englesbe MJ, Guillamondegui OD, Hines LH, Cofer JB, Flum DR, Thirlby RC, Kazaure HS, Wren SM, O'Leary KJ, Thurk JL, Kennedy GD, Tevis SE, Yang AD. Process improvement in surgery. Curr Probl Surg. 2016 Feb;53(2):62-96. https://www.ncbi.nlm.nih.gov/pubmed/26806271
  • Nepomnayshy D, Alseidi AA, Fitzgibbons SC, Stefanidis D. Identifying the need for and content of an advanced laparoscopic skills curriculum: results of a national survey. Am J Surg. 2016 Feb;211(2):421-5. https://www.ncbi.nlm.nih.gov/pubmed/26686906
  • Weiss A, Hollandsworth HM, Alseidi A, Scovel L, French C, Derrick EL, Klaristenfeld D. Environmentalism in surgical practice. Curr Probl Surg. 2016 Apr;53(4):165-205. https://www.ncbi.nlm.nih.gov/pubmed/27102336
  • Deal SB, Lendvay TS, Haque MI, Brand T, Comstock B, Warren J, Alseidi A. Crowd-sourced assessment of technical skills: an opportunity for improvement in the assessment of laparoscopic surgical skills. Am J Surg. 2016 Feb;211(2):398-404. https://www.ncbi.nlm.nih.gov/pubmed/26709011

Liver Disorders

  • Kowdley KV, Nelson DR, Lalezari JP, Box T, Gitlin N, Poleynard G, Rabinovitz M, Ravendhran N, Sheikh AM, Siddique A, Bhore R, Noviello S, Rana K. On-treatment HCV RNA as a predictor of sustained virological response in HCV genotype 3-infected patients treated with daclatasvir and sofosbuvir. Liver Int. 2016 Nov;36(11):1611-1618. doi: 10.1111/liv.13165. https://www.ncbi.nlm.nih.gov/pubmed/27188960
  • Perini MV, Coelho FF, Kruger JA, Rocha FG, Herman P. Extended right hepatectomy with caudate lobe resection using the hilar "en bloc" resection technique with a modified hanging maneuver. Surg Oncol. 2016 Mar;113(4):427-31. doi: 10.1002/jso.24154. https://www.ncbi.nlm.nih.gov/pubmed/26776500

Pancreatic-Biliary System

  • Alemi F, Rocha FG, Helton WS, Biehl T, Alseidi A. Classification and techniques of en bloc venous reconstruction for pancreaticoduodenectomy. HPB (Oxford) 2016;18(10):827-834. https://www.ncbi.nlm.nih.gov/pubmed/27506994
  • Dissanaike S., Alseidi A. (2016). “When a Good Lap Chole Turns Bad. The Surgical Approach to Severe Cholecystitis: Is It Time for an Overhaul?” In General Surgery News. p. 1. Feb,2016. http://www.generalsurgerynews.com/Opinions-Letters/Article/02-16/When-a-Good-Lap-Chole-Turns-Bad/35217/ses=ogst
  • Jutric Z, Johnston WC, Grendar J, Haykin L, Mathews C, Harmon LK, Shen J, Hahn HP, Coy DL, Cassera MA, Helton WS, Rocha FG, Wolf RF, Hansen PD, Hammill CW, Alseidi AA, Newell PH. Preoperative computed tomography scan to predict pancreatic fistula after distal pancreatectomy using gland and tumor characteristics. Am J Surg. 2016 May;211(5):871-6. https://www.ncbi.nlm.nih.gov/pubmed/27046794
  • Rose JB, Correa-Gallego C, Li Y, Nelson J, Alseidi A, Helton WS, Allen PJ, D'Angelica MI, DeMatteo RP, Fong Y, Kingham TP, Kowdley KV, Jarnagin WR, Rocha FG. The Role of Biliary Carcinoembryonic Antigen-Related Cellular Adhesion Molecule 6 (CEACAM6) as a Biomarker in Cholangiocarcinoma. PLoS One. 2016 Mar 14;11(3):e0150195. https://www.ncbi.nlm.nih.gov/pubmed/26974538

Pancreatic Disease

  • Blayney MJ, Nguyen A, Aboulafia DM. Diagnosis and management of a pancreaticopleural fistula in a patient with AIDS and a large pleural effusion. J Int Assoc Provid AIDS Care 2016;15(6):459-462. https://www.ncbi.nlm.nih.gov/pubmed/27655836

  • Hagensen A, London AE, Phillips JJ, Helton WS, Picozzi VJ, Blackmore CC. Using experience-based design to improve the care experience for patients with pancreatic cancer J Oncol Pract 2016;12(12):e1035-e1041. https://www.ncbi.nlm.nih.gov/pubmed/27624947
  • Oh SY, Edwards A, Mandelson MT, Hahn H, Alseidi A, Biehl T, Kozarek RA, Rocha FG, Helton S, Picozzi VJ. Localized pancreatic cancer with positive peritoneal cytology as a sole manifestation of metastatic disease: a single-institution experience. Am J Surg 2016; (16):30283-5. https://www.ncbi.nlm.nih.gov/pubmed/27424044
  • Oh SY, Irani S, Kozarek KA. Cystic neoplasms of the pancreas: Where do we stand? J Hepatol Gastroint Dis 2016;2:140 https://www.omicsonline.org/open-access/cystic-neoplasms-of-the-pancreas-where-do-we-stand.php?aid=84037
  • Oh SY, Irani S, Kozarek RA. What are the current and potential future roles for endoscopic ultrasound in the treatment of pancreatic cancer? World J Gastrointest Endosc. 2016 Apr 10;8(7):319-29. https://www.ncbi.nlm.nih.gov/pubmed/27076870
  • Pishvaian MJ, Bender RJ, Matrisian LM, Rahib L, Hendifar A, Hoos WA, Mikhail S, Chung V, Picozzi V, Heartwell C, Mason K, Varieur K, Aberra M, Madhavan S, Petricoin E 3rd, Brody JR.
  • A pilot study evaluating concordance between blood-based and patient-matched tumor molecular testing within pancreatic cancer patients participating in the Know Your Tumor (KYT) initiative. Oncotarget. 2016 Nov 8. https://www.ncbi.nlm.nih.gov/pubmed/27833075
  • Rocha FG, Hashimoto Y, Traverso LW, Dorer R, Kozarek R, Helton WS, Picozzi VJ. Interferon-based Adjuvant Chemoradiation for Resected Pancreatic Head Cancer: Long-term Follow-up of the Virginia Mason Protocol. Ann Surg. 2016 Feb;263(2):376-84. https://www.ncbi.nlm.nih.gov/pubmed/25775069

Small Bowel

Therapeutic Endoscopy

  • DaVee T, Irani S, Leggett CL, Berzosa Corella M, Grooteman KV, Wong Kee Song LM, Wallace MB, Kozarek RA, Baron TH. Stent-in-stent technique for removal of embedded partially covered self-expanding metal stents. Surg Endosc. 2016 Jun;30(6):2332-41. https://www.ncbi.nlm.nih.gov/pubmed/26416379
  • Freeman ML, Kozarek RA. Take 2 indomethacin (suppositories) and call me in the morning? The role of nonsteroidal anti-inflammatory drugs in protection against post-endoscopic retrograde cholangiopancreatography pancreatitis. Gastroenterology 2016;150(4):805-808. https://experts.umn.edu/en/publications/take-2-indomethacin-suppositories-and-call-me-in-the-morning-the-
  • Higa JT, Gluck M, Ross AS. Duodenoscope-Associated Bacterial Infections: A Review and Update. Curr Treat Options Gastroenterol. 2016 Jun;14(2):185-93. https://www.ncbi.nlm.nih.gov/pubmed/27020265
  • Irani S, Jalaj S, Ross A, Larsen M, Grimm IS, Baron TH. Use of a lumen-apposing metal stent to treat GI strictures (with videos). Gastrointest Endosc 2016;(E-pub ahead of print). https://www.ncbi.nlm.nih.gov/pubmed/27633158
  • Irani S, Ngamruengphong S, TEOH A, Will U, Nieto J, Abu Dayyeh BK, Gan S, Larsen M, Chi Yip H, Topazian MD, Levy MJ, Thompson CC, Storm AC, Hajiyeva G, Ismail A, Chen Y, Bukhari M, Chavez YH C, Kumbhari V, Khashab MA. Similar efficacies of endoscopic ultrasound gallbladder drainage with a lumen-apposing metal stent vs percutaneous transhepatic gallbladder drainage for acute cholecystitis. Clin Gastroenterol Hepatol 2016 Dec 30. Pii: S1542-3565(16)31245-0 (E-pub ahead of print.). http://www.cghjournal.org/article/S1542-3565(16)31246-0/abstract
  • Ende AR, Irani S, Kozarek RA. Symptomatic pancreatic duct stones in the disconnected bile duct: a case series. Pancreatology 2017 Jan - Feb;17(1):51-54. (E-pub ahead of print.) 2016 Nov 14. http://ow.ly/B7J0309NF9q
  • Irani S, Kozarek RA. The buried lumen-apposing metal stent: Is this a stent problem, a location problem, or both? VideoGIE, 2016;1:25-26. http://www.videogie.org/article/S2468-4481(16)30008-X/pdf
  • Itoi T, Baron TH, Mouen K, Tsuchiya T, Irani S, Dhir V, Teoh AY. Technical review of EUS-guided gastroenterostomy in 2017. Dig Endosc 2016;(E-pub ahead of print.). http://onlinelibrary.wiley.com/doi/10.1111/den.12794/full
  • Khashab MA, El Zein MH, Sharzehi K, Marson FP, Haluszka O, Small AJ, Nakai Y, Park DH, Kunda R, Teoh AY, Peñas I, Perez-Miranda M, Kumbhari V, Van der Merwe S, Artifon EL, Ross AS. EUS-guided biliary drainage or enteroscopy-assisted ERCP in patients with surgical anatomy and biliary obstruction: an international comparative study. Endosc Int Open 2016;4(12):E1322-E1327. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161123/
  • Kim TH, Kim JH, Seo DW, Lee DK, Reddy ND, Rerknimitr R, Ratanachu-Ek T, Khor CJ, Itoi T, Yasuda I, Isayama H, Lau JY, Wang HP, Chan HH, Hu B, Kozarek RA, Baron TH. International consensus guidelines for endoscopic papillary large-balloon dilation. Gastrointest Endosc. 2016 Jan;83(1):37-47. https://www.ncbi.nlm.nih.gov/pubmed/26232360
  • Larsen M, Kozarek RA. Management of Disconnected Pancreatic Duct Syndrome. Management of disconnected pancreatic duct syndrome. Curr Treat Options Gastroenterol 2016;14(3):348-359. https://www.ncbi.nlm.nih.gov/pubmed/27392638
  • Petersen BT, Koch J, Ginsberg GG. Infection Using ERCP Endoscopes. Gastroenterology. 2016 Jul;151(1):46-50. http://www.gastrojournal.org/article/S0016-5085(16)34532-2/abstract
  • Ross AS. Enhanced methods for duodenoscope reprocessing: answers or just more questions. Gastrointest Endosc. 2016 Aug;84(2):263-5. https://www.ncbi.nlm.nih.gov/pubmed/27425799
  • Rustagi T, Irani S, Reddy DN, Abu Dayyeh BK, Baron TH, Gostout CJ, Levy MJ, Martin J, Petersen BT, Ross A, Topazian MD. Radiofrequency ablation for intraductal extension of ampullary neoplasms. Gastrointest Endosc. 2016 Nov 17. pii: S0016-5107(16)30738-6. https://www.ncbi.nlm.nih.gov/pubmed/27866907

Book Chapters

Thoracic Surgery

  • Blackmon SH, Cooke DT, Whyte R, Miller D, Cerfolio R, Farjah F, Rocco G, Blum M, Hazelrigg S, Howington J, Low D, Swanson S, Fann JI, Ikonomidis JS, Wright C, Grondin SC. The Society of Thoracic Surgeons Expert Consensus Statement: A Tool Kit to Assist Thoracic Surgeons Seeking Privileging to Use New Technology and Perform Advanced Procedures in General Thoracic Surgery. Ann Thorac Surg. 2016 Mar;101(3):1230-7. https://www.ncbi.nlm.nih.gov/pubmed/27124326
  • Cattoni M, Vallieres E, Brown LM, Sarkeshik AA, Margaritora S, Siciliani A, Filosso PL, Guerrera F, Imperatori A, Rotolo N, Farjah F, Wandell G, Costas K, Mann C, Hubka M, Kaplan S, Farivar AS, Aye RW, Louie B. PS01.25: large cell neuroendocrine carcinoma of the lung: prognostic factors of survival and recurrence after RO surgical resection: topic: surgery. J Thorac Oncol 2016;11(11S):S284.
  • Pozzi A, El Lakis MA, Chamieh J, Carbonell BB, Villa F. The typical presentation spectrum of deep vein thrombosis associated with inferior vena cava malformations. Thrombosis 2016;2016:4965458. https://www.hindawi.com/journals/thrombosis/2016/4965458/
  • Schmidt HM, El Lakis MA, Markar SR, Hubka M, Low DE. Accelerated recovery within standardized recovery pathways after esophagectomy: a prospective cohort study assessing the effects of early discharge on outcomes, readmissions, patient satisfaction, and costs. Ann Thorac Surg 2016;102(3):931-939.
  • Schmidt HM, Mohiuddin K, Bodnar AM, El Lakis M, Kaplan S, Irani S, Gan I, Ross A, Low DE. Multidisciplinary treatment of T1a adenocarcinoma in Barrett's esophagus: contemporary comparison of endoscopic and surgical treatment in physiologically fit patients. Surg Endosc. 2016 Aug;30(8):3391-401. https://www.ncbi.nlm.nih.gov/pubmed/26541725
  • Sepesi B, Schmidt HE, Lada M, Correa AM, Walsh GL, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Ajani JA, Watson TJ, Swisher SG, Low DE, Hofstetter WL. Survival in Patients With Esophageal Adenocarcinoma Undergoing Trimodality Therapy Is Independent of Regional Lymph Node Location. Ann Thorac Surg. 2016 Mar;101(3):1075-80; Discussion 1080-1. https://www.ncbi.nlm.nih.gov/pubmed/26680311

Archived Articles